Protein Quality Control in Heart Disease
نویسندگان
چکیده
منابع مشابه
Quality of life in patients with ischemic heart disease
Background and Purpose: Ischemic Heart Diseases (IHD) is getting as the most common and the main causes of heart diseases and mortalities worldwide affecting the quality of life (QOL) of the patients. This study was conducted to determine the QOL for the patients with IHD referring to medical centers of Kashan in 2007. Methods: This cross-sectional study was performed on all patients (n =500) ...
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Exercise training is a well-known coadjuvant in heart failure treatment; however, the molecular mechanisms underlying its beneficial effects remain elusive. Despite the primary cause, heart failure is often preceded by two distinct phenomena: mitochondria dysfunction and cytosolic protein quality control disruption. The objective of the study was to determine the contribution of exercise traini...
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Single nucleotide polymorphisms in the ubiquilin-1 gene may confer risk for late-onset Alzheimer disease (AD). We have shown previously that ubiquilin-1 functions as a molecular chaperone for the amyloid precursor protein (APP) and that protein levels of ubiquilin-1 are decreased in the brains of AD patients. We have recently found that ubiquilin-1 regulates APP trafficking and subsequent secre...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2010
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2010.03.101